Кевин ХартGeorge (voice)
Томас МиддлдитчHarold (voice)
Эд ХелмсCaptain Underpants / Mr. Krupp (voice)
Ник КроллProfessor Poopypants (voice)
Джордан ПилMelvin (voice)
Кристен ШаалEdith (voice)
DeeDee RescherMs. Ribble (voice)
Брайан ПосенMr. Rected (voice)
David SorenTommy (voice)
Mel RodriguezMr. Fyde (voice)
Линнанне ЗагерGeorge's Mom (voice)
Tiffany Lauren BennickeSad Girl (voice)
James RyanMime (voice)
Лесли Дэвид БейкерOfficer McPiggly (voice)
Шуга Лин БирдGoodie Two-Shoes Girl (voice)
Лесли НиколNobel Moderator (voice)
Крис МиллерNobel Audience Member (voice)