Keir DulleaDr. David Bowman
Gary LockwoodDr. Frank Poole
William SylvesterDr. Heywood Floyd
Douglas RainHAL 9000 (voice)
Daniel RichterMoonwatcher
Leonard RossiterDr. Andrei Smyslov
Margaret TyzackElena
Robert BeattyDr. Ralph Halvorsen
Ed BishopAries-1B Lunar Shuttle Captain
Гленн БекAstronaut
Alan GiffordPoole's Father
Ann GillisPoole's Mother
Edwina CarrollAries-1B Stewardess
Penny BrahmsStewardess
David CharkhamApe
Maggie LondonHostess in Elevator (uncredited)
Chela MatthisonReceptionist (uncredited)
Vivian KubrickFloyd's Daughter (uncredited)
Kenneth KendallBBC-12 Announcer (uncredited)
Kevin ScottMiller (uncredited)
Бернелл ТакерTMA-1 Site Photographer (uncredited)
John SwindellsTMA-1 Site Technician #1 (uncredited)
Стэнли КубрикAstronaut Breathing (voice) (uncredited)